3D-bioprinted synthetic hydrogel for liver transplantation

A fully synthetic PEG-based hydrogel is 3D-bioprinted along with a biocompatible sacrificial material that is used to create channels in the printed construct. The channels will then allow for the formation of a vascular network inside the hydrogel. This construct is an essential block in the ORGANTRANS project in the creation of a liver tissue 3D printing platform which aims to replace liver transplantation for end-stage liver failure patients. Additionally, this platform can be scaled to other organ systems, as organoid technology is one of the largest parts of regenerative medicine.