Revolutionizing Organ Transplants: THE ORGANTRANS

6 countries

8 Partners

42 months of intensive work

62 key deliverables

6 720 working hours

This is ORGANTRANS: Controlled Organoids transplantation as enabler for regenerative medicine translation.

Within the realms of the EU-funded ORGANTRANS project, experts have developed an alternative that can change the landscape of organ transplantation as we know it. This pioneering method harnesses the power of bioengineering, 3D bioprinting and stem cells to craft new liver tissue within laboratory conditions.

It is known, that liver diseases account for 1 million deaths worldwide every year. While liver transplantation is the most effective way to restore normal functions for various diseases acute Liver failure, inherited metabolic disease and chronic liver failure, less than 30 % of global transplantation needs are currently met.

The ORGANTRANS project potentially offers a lifeline to those in dire need. It covered the entire development cycle from cell source to tissue engineering. This innovative process revolves around utilizing a patient’s own healthy cells to cultivate new liver tissue in controlled laboratory settings The building blocks such as the spheroid sorting platform, bioink, 3D bioprinting, and the maturation platform were meticulously synchronized and integrated into one 3D liver tissue bioprinting platform, paving the way for the development of a functional liver construct.

Moreover, the ORGANTRANS project’s impact is not confined to liver transplantation alone, it has opened the door to innovative technologies that have the potential to revolutionize other organ systems and tissues within the field of regenerative medicine.

Watch a short video about the ORGANTRANS project and the incredible innovations achieved within this groundbreaking initiative.